The clinical application of SNP-based next-generation sequencing (SNP-NGS) for evaluation of chimerism and microchimerism after HLA-mismatched stem cell microtransplantation

Genetic diagnostic methods for evaluation of chimerism after HSCT, such as STR-PCR and XY-FISH, have limited sensitivity. When donor chimerism is in the micro range (< 1%), deviations in the accuracy of assessment are the most significant disadvantage of these common methods. We developed a highl...

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Detalles Bibliográficos
Autores principales: Li, Weiyang, Xu, Yi, Feng, Yufeng, Zhou, Haixia, Ma, Xiao, Wu, Depei, Chen, Suning, Sun, Aining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588463/
https://www.ncbi.nlm.nih.gov/pubmed/35802296
http://dx.doi.org/10.1007/s12185-022-03415-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588463/
https://www.ncbi.nlm.nih.gov/pubmed/35802296
http://dx.doi.org/10.1007/s12185-022-03415-8

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