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High DKK3 expression related to immunosuppression was associated with poor prognosis in glioblastoma: machine learning approach

BACKGROUND: Glioblastoma multiforme (GBM) is an aggressive malignant primary brain tumor. Wnt/β-catenin is known to be related to GBM stemness. Cancer stem cells induce immunosuppressive and treatment resistance in GBM. We hypothesized that Wnt/β-catenin-related genes with immunosuppression could be...

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Detalles Bibliográficos
Autores principales: Han, Myung-Hoon, Min, Kyueng-Whan, Noh, Yung-Kyun, Kim, Jae Min, Cheong, Jin Hwan, Ryu, Je Il, Won, Yu Deok, Koh, Seong-Ho, Myung, Jae Kyung, Park, Ji Young, Kwon, Mi Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588473/
https://www.ncbi.nlm.nih.gov/pubmed/35599254
http://dx.doi.org/10.1007/s00262-022-03222-4