Tumor-derived IL-8 facilitates lymph node metastasis of gastric cancer via PD-1 up-regulation in CD8(+) T cells

BACKGROUND: The pretherapeutic serum interleukin-8 (sIL-8) levels have been revealed to be increased in about half of patients with locally advanced gastric cancer. However, the roles of IL-8 in lymph node metastasis (LNM) and the underlying mechanisms remain unclear. METHODS: 146 patients with prim...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Zhai, Jing, Shen, Yuke, Zhang, Tiancheng, Wang, Yaohui, He, Yani, You, Qiang, Shen, Lizong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588474/
https://www.ncbi.nlm.nih.gov/pubmed/35633411
http://dx.doi.org/10.1007/s00262-022-03223-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588474/
https://www.ncbi.nlm.nih.gov/pubmed/35633411
http://dx.doi.org/10.1007/s00262-022-03223-3

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