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SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca(2+)
Post‐translational modification of the myofilament protein troponin I by phosphorylation is known to trigger functional changes that support enhanced contraction and relaxation of the heart. We report for the first time that human troponin I can also be modified by SUMOylation at lysine 177. Functio...
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588612/ https://www.ncbi.nlm.nih.gov/pubmed/35633070 http://dx.doi.org/10.1111/febs.16537 |