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Expanding Catch and Release DNA Decoy (CRDD) Technology with Pyrimidine Mimics

Catch and release DNA decoys (CRDDs) utilize photochemically responsive nucleoside analogues that generate abasic sites upon exposure to light. Herein, we describe the synthesis and evaluation of four candidate CRDD monomers containing nucleobases that mimic endogenous pyrimidines: 2‐nitroimidazole...

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Detalles Bibliográficos
Autores principales: Kennelly, Samantha A., Moorthy, Ramkumar, Otero, Ruben Silva, Harki, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588621/
https://www.ncbi.nlm.nih.gov/pubmed/35849314
http://dx.doi.org/10.1002/chem.202201355