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Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome
Pancreatic ductal adenocarcinoma (PDAC) is a highly desmoplastic, aggressive cancer that frequently progresses and spreads by metastasis to the liver(1). Cancer-associated fibroblasts, the extracellular matrix and type I collagen (Col I) support(2,3) or restrain the progression of PDAC and may imped...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588640/ https://www.ncbi.nlm.nih.gov/pubmed/36198801 http://dx.doi.org/10.1038/s41586-022-05169-z |