MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways

CD95 is a death receptor that can promote oncogenesis through molecular mechanisms that are not fully elucidated. Although the mature CD95 membrane receptor is considered to start with the arginine at position 17 after elimination of the signal peptide, this receptor can also be cleaved by MMP7 upst...

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Detalles Bibliográficos
Autores principales: Kenji, Shoji F., Kurma, Keerthi, Collet, Brigitte, Oblet, Christelle, Debure, Laure, Di Primo, Carmelo, Minder, Laëtitia, Vérité, Franck, Danger, Yannic, Jean, Mickael, Penna, Aubin, Levoin, Nicolas, Legembre, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588774/
https://www.ncbi.nlm.nih.gov/pubmed/36274061
http://dx.doi.org/10.1038/s41419-022-05352-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588774/
https://www.ncbi.nlm.nih.gov/pubmed/36274061
http://dx.doi.org/10.1038/s41419-022-05352-0

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