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MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways
CD95 is a death receptor that can promote oncogenesis through molecular mechanisms that are not fully elucidated. Although the mature CD95 membrane receptor is considered to start with the arginine at position 17 after elimination of the signal peptide, this receptor can also be cleaved by MMP7 upst...
Autores principales: | Kenji, Shoji F., Kurma, Keerthi, Collet, Brigitte, Oblet, Christelle, Debure, Laure, Di Primo, Carmelo, Minder, Laëtitia, Vérité, Franck, Danger, Yannic, Jean, Mickael, Penna, Aubin, Levoin, Nicolas, Legembre, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588774/ https://www.ncbi.nlm.nih.gov/pubmed/36274061 http://dx.doi.org/10.1038/s41419-022-05352-0 |
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