A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis

Ferroptosis is a type of lipid peroxidation-dependent cell death that is emerging as a therapeutic target for cancer. However, the mechanisms of ferroptosis during the generation and detoxification of lipid peroxidation products remain rather poorly defined. Here, we report an unexpected role for th...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Huang, Jun, Yu, Chunhua, Liu, Jiao, Gao, Wanli, Li, Jingbo, Song, Xinxin, Zhou, Zhuan, Li, Changfeng, Xie, Yangchun, Kroemer, Guido, Liu, Jinbao, Tang, Daolin, Kang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588786/
https://www.ncbi.nlm.nih.gov/pubmed/36274088
http://dx.doi.org/10.1038/s41467-022-34096-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588786/
https://www.ncbi.nlm.nih.gov/pubmed/36274088
http://dx.doi.org/10.1038/s41467-022-34096-w

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