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A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis
Ferroptosis is a type of lipid peroxidation-dependent cell death that is emerging as a therapeutic target for cancer. However, the mechanisms of ferroptosis during the generation and detoxification of lipid peroxidation products remain rather poorly defined. Here, we report an unexpected role for th...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588786/ https://www.ncbi.nlm.nih.gov/pubmed/36274088 http://dx.doi.org/10.1038/s41467-022-34096-w |