Cargando…

Clinical application of prion-like seeding in α-synucleinopathies: Early and non-invasive diagnosis and therapeutic development

The accumulation and deposition of misfolded α-synuclein (α-Syn) aggregates in the brain is the central event in the pathogenesis of α-synucleinopathies, including Parkinson’s disease, dementia with Lewy bodies, and multiple-system atrophy. Currently, the diagnosis of these diseases mainly relies on...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jiaqi, Luo, Haiyang, Zheng, Honglin, Duan, Suying, Zhao, Taiqi, Yuan, Yanpeng, Liu, Yutao, Zhang, Xiaoyun, Wang, Yangyang, Yang, Jing, Xu, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588983/
https://www.ncbi.nlm.nih.gov/pubmed/36299857
http://dx.doi.org/10.3389/fnmol.2022.975619