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Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes

The gut microbiota is crucial in the regulation of bile acid (BA) metabolism. However, not much is known about the regulation of BAs during progression to type 1 diabetes (T1D). Here, we analyzed serum and stool BAs in longitudinal samples collected at 3, 6, 12, 18, 24, and 36 months of age from chi...

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Detalles Bibliográficos
Autores principales: Lamichhane, Santosh, Sen, Partho, Dickens, Alex M., Alves, Marina Amaral, Härkönen, Taina, Honkanen, Jarno, Vatanen, Tommi, Xavier, Ramnik J., Hyötyläinen, Tuulia, Knip, Mikael, Orešič, Matej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589006/
https://www.ncbi.nlm.nih.gov/pubmed/36195095
http://dx.doi.org/10.1016/j.xcrm.2022.100762