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Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes
The gut microbiota is crucial in the regulation of bile acid (BA) metabolism. However, not much is known about the regulation of BAs during progression to type 1 diabetes (T1D). Here, we analyzed serum and stool BAs in longitudinal samples collected at 3, 6, 12, 18, 24, and 36 months of age from chi...
Autores principales: | Lamichhane, Santosh, Sen, Partho, Dickens, Alex M., Alves, Marina Amaral, Härkönen, Taina, Honkanen, Jarno, Vatanen, Tommi, Xavier, Ramnik J., Hyötyläinen, Tuulia, Knip, Mikael, Orešič, Matej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589006/ https://www.ncbi.nlm.nih.gov/pubmed/36195095 http://dx.doi.org/10.1016/j.xcrm.2022.100762 |
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