Polygenic power calculator: Statistical power and polygenic prediction accuracy of genome-wide association studies of complex traits

Power calculation is a necessary step when planning genome-wide association studies (GWAS) to ensure meaningful findings. Statistical power of GWAS depends on the genetic architecture of phenotype, sample size, and study design. While several computer programs have been developed to perform power ca...

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Detalles Bibliográficos
Autores principales: Wu, Tian, Liu, Zipeng, Mak, Timothy Shin Heng, Sham, Pak Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589038/
https://www.ncbi.nlm.nih.gov/pubmed/36299579
http://dx.doi.org/10.3389/fgene.2022.989639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589038/
https://www.ncbi.nlm.nih.gov/pubmed/36299579
http://dx.doi.org/10.3389/fgene.2022.989639

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