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FOXO1 inhibits FSL-1 regulation of integrin β6 by blocking STAT3 binding to the integrin β6 gene promoter

Integrin β6 (ITGB6), an epithelial-specific receptor, is downregulated in the gingival epithelium of periodontitis and is associated with inflammation response and periodontitis development. However, the transcriptional regulatory mechanism of ITGB6 downregulation in the human gingival epithelium re...

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Detalles Bibliográficos
Autores principales: Xu, Mingyan, Huang, Jie, Zhu, Feixiang, Shen, Kailun, Liu, Fan, Deng, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589051/
https://www.ncbi.nlm.nih.gov/pubmed/36299623
http://dx.doi.org/10.3389/fcimb.2022.998693