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Gut microbiota-derived indole 3-propionic acid partially activates aryl hydrocarbon receptor to promote macrophage phagocytosis and attenuate septic injury

Sepsis is associated with a high risk of death, and the crosstalk between gut microbiota and sepsis is gradually revealed. Indole 3-propionic acid (IPA) is a gut microbiota-derived metabolite that exerts immune regulation and organ protective effects. However, the role of IPA in sepsis is not clear....

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Detalles Bibliográficos
Autores principales: Huang, Zhi-Bin, Hu, Zhen, Lu, Chen-Xin, Luo, Si-Dan, Chen, Yu, Zhou, Zhi-Peng, Hu, Jing-Juan, Zhang, Fang-Ling, Deng, Fan, Liu, Ke-Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589056/
https://www.ncbi.nlm.nih.gov/pubmed/36299625
http://dx.doi.org/10.3389/fcimb.2022.1015386