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Involvement of ceramide biosynthesis in increased extracellular vesicle release in Pkd1 knock out cells

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited disorder characterized by the development of renal cysts, which frequently leads to renal failure. Hypertension and other cardiovascular symptoms contribute to the high morbidity and mortality of the disease. ADPKD is caused by mut...

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Detalles Bibliográficos
Autores principales: Carotti, Valentina, van der Wijst, Jenny, Verschuren, Eric H. J., Rutten, Luco, Sommerdijk, Nico, Kaffa, Charlotte, Sommers, Vera, Rigalli, Juan P., Hoenderop, Joost G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589111/
https://www.ncbi.nlm.nih.gov/pubmed/36299464
http://dx.doi.org/10.3389/fendo.2022.1005639