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Involvement of ceramide biosynthesis in increased extracellular vesicle release in Pkd1 knock out cells
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited disorder characterized by the development of renal cysts, which frequently leads to renal failure. Hypertension and other cardiovascular symptoms contribute to the high morbidity and mortality of the disease. ADPKD is caused by mut...
Autores principales: | Carotti, Valentina, van der Wijst, Jenny, Verschuren, Eric H. J., Rutten, Luco, Sommerdijk, Nico, Kaffa, Charlotte, Sommers, Vera, Rigalli, Juan P., Hoenderop, Joost G. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589111/ https://www.ncbi.nlm.nih.gov/pubmed/36299464 http://dx.doi.org/10.3389/fendo.2022.1005639 |
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