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Integrated analysis of bulk and single-cell RNA-seq reveals the role of MYC signaling in lung adenocarcinoma

MYC is one of the well-known oncogenes, and its important role in cancer still remains largely unknown. We obtained lung adenocarcinoma (LUAD) multi-omics data including genome, transcriptome, and single-cell sequencing data from multiple cohorts. We calculated the GSVA score of the MYC target v1 us...

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Detalles Bibliográficos
Autores principales: Hao, Lu, Chen, Qiuyan, Chen, Xi, Zhou, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589149/
https://www.ncbi.nlm.nih.gov/pubmed/36299592
http://dx.doi.org/10.3389/fgene.2022.1021978