Cargando…

Natural polyphenols convert proteins into histone-binding ligands

Antioxidants are sensitive to oxidation and are immediately converted into their oxidized forms that can react with proteins. We have recently found that proteins incubated with oxidized vitamin C (dehydroascorbate) gain a new function as a histone-binding ligand. This finding led us to predict that...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamaguchi, Kosuke, Itakura, Masanori, Tsukamoto, Mona, Lim, Sei-Young, Uchida, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589214/
https://www.ncbi.nlm.nih.gov/pubmed/36162500
http://dx.doi.org/10.1016/j.jbc.2022.102529