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Natural polyphenols convert proteins into histone-binding ligands
Antioxidants are sensitive to oxidation and are immediately converted into their oxidized forms that can react with proteins. We have recently found that proteins incubated with oxidized vitamin C (dehydroascorbate) gain a new function as a histone-binding ligand. This finding led us to predict that...
Autores principales: | Yamaguchi, Kosuke, Itakura, Masanori, Tsukamoto, Mona, Lim, Sei-Young, Uchida, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589214/ https://www.ncbi.nlm.nih.gov/pubmed/36162500 http://dx.doi.org/10.1016/j.jbc.2022.102529 |
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