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Glucocorticoid receptor dysregulation underlies 5-HT(2A)R-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model

Prenatal environmental insults increase the risk of neurodevelopmental psychiatric conditions in the offspring. Structural modifications of dendritic spines are central to brain development and plasticity. Using maternal immune activation (MIA) as a rodent model of prenatal environmental insult, pre...

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Detalles Bibliográficos
Autores principales: Saunders, Justin M., Muguruza, Carolina, Sierra, Salvador, Moreno, José L., Callado, Luis F., Meana, J. Javier, Beardsley, Patrick M., González-Maeso, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589215/
https://www.ncbi.nlm.nih.gov/pubmed/36100039
http://dx.doi.org/10.1016/j.jbc.2022.102481