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Glucocorticoid receptor dysregulation underlies 5-HT(2A)R-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model
Prenatal environmental insults increase the risk of neurodevelopmental psychiatric conditions in the offspring. Structural modifications of dendritic spines are central to brain development and plasticity. Using maternal immune activation (MIA) as a rodent model of prenatal environmental insult, pre...
Autores principales: | Saunders, Justin M., Muguruza, Carolina, Sierra, Salvador, Moreno, José L., Callado, Luis F., Meana, J. Javier, Beardsley, Patrick M., González-Maeso, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589215/ https://www.ncbi.nlm.nih.gov/pubmed/36100039 http://dx.doi.org/10.1016/j.jbc.2022.102481 |
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