Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy

Camptothecin (CPT) has attracted much attention due to its potent antitumor activities. However, the undesirable physicochemical properties, including poor water solubility, unstable lactone ring, and severe adverse effects, limit its further application. In this study, two water-soluble prodrugs, C...

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Detalles Bibliográficos
Autores principales: Guo, Zhaopei, Wang, Zian, Liang, Ruifeng, Tian, Huayu, Chen, Xuesi, Chen, Meiwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589304/
https://www.ncbi.nlm.nih.gov/pubmed/35801419
http://dx.doi.org/10.17305/bjbms.2022.7194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589304/
https://www.ncbi.nlm.nih.gov/pubmed/35801419
http://dx.doi.org/10.17305/bjbms.2022.7194

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