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Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy
Camptothecin (CPT) has attracted much attention due to its potent antitumor activities. However, the undesirable physicochemical properties, including poor water solubility, unstable lactone ring, and severe adverse effects, limit its further application. In this study, two water-soluble prodrugs, C...
Autores principales: | Guo, Zhaopei, Wang, Zian, Liang, Ruifeng, Tian, Huayu, Chen, Xuesi, Chen, Meiwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589304/ https://www.ncbi.nlm.nih.gov/pubmed/35801419 http://dx.doi.org/10.17305/bjbms.2022.7194 |
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