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Matrix metalloproteinase-7 is increased in lung bases but not apices in idiopathic pulmonary fibrosis

INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a progressively fibrotic lung condition with poor prognosis. Matrix metalloproteinase-7 (MMP7) is a protein secreted by epithelial cells in IPF lungs. It is not known if MMP7 expression correlates with fibrotic changes in lung tissue. METHODS: Tis...

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Detalles Bibliográficos
Autores principales: Jaffar, Jade, Wong, Mae, Fishbein, Gregory A., Alhamdoosh, Monther, McMillan, Laura, Gamell-Fulla, Cristina, Ng, Milica, Wilson, Nick, Symons, Karen, Glaspole, Ian, Westall, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589331/
https://www.ncbi.nlm.nih.gov/pubmed/36299365
http://dx.doi.org/10.1183/23120541.00191-2022