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PARK2 Induces Osteoclastogenesis through Activation of the NF-κB Pathway

Osteoclast generation from monocyte/macrophage lineage precursor cells needs to be tightly regulated to maintain bone homeostasis and is frequently over-activated in inflammatory conditions. PARK2, a protein associated with Parkinson’s disease, plays an important role in mitophagy via its ubiquitin...

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Detalles Bibliográficos
Autores principales: Hong, Seo Jin, Jung, Suhan, Jang, Ji Sun, Mo, Shenzheng, Kwon, Jun-Oh, Kim, Min Kyung, Kim, Hong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589368/
https://www.ncbi.nlm.nih.gov/pubmed/36047447
http://dx.doi.org/10.14348/molcells.2022.0058