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SF3B4 Depletion Retards the Growth of A549 Non-Small Cell Lung Cancer Cells via UBE4B-Mediated Regulation of p53/p21 and p27 Expression

Splicing factor B subunit 4 (SF3B4), a component of the U2-pre-mRNA spliceosomal complex, contributes to tumorigenesis in several types of tumors. However, the oncogenic potential of SF3B4 in lung cancer has not yet been determined. The in vivo expression profiles of SF3B4 in non-small cell lung can...

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Detalles Bibliográficos
Autores principales: Kim, Hyungmin, Lee, Jeehan, Jung, Soon-Young, Yun, Hye Hyeon, Ko, Jeong-Heon, Lee, Jeong-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589371/
https://www.ncbi.nlm.nih.gov/pubmed/35996826
http://dx.doi.org/10.14348/molcells.2022.0037