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TSH−SPP1/TRβ−TSH positive feedback loop mediates fat deposition of hepatocyte: Crosstalk between thyroid and liver

AIMS: We conducted this study with two aims: (1) whether TRβ could be damaged by NAFLD, thereby represent thyroid hormone resistance-like manifestation and (2) to analyze the potential role of SPP1 in TH signaling pathway on the process of NAFLD. This study is expected to provide a new perspective o...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Wen, Wenjie, Ye, Shandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589424/
https://www.ncbi.nlm.nih.gov/pubmed/36300106
http://dx.doi.org/10.3389/fimmu.2022.1009912