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Insulin-induced mTOR signaling and gluconeogenesis in renal proximal tubules: A mini-review of current evidence and therapeutic potential

Energy is continuously expended in the body, and gluconeogenesis maintains glucose homeostasis during starvation. Gluconeogenesis occurs in the liver and kidneys. The proximal tubule is the primary location for renal gluconeogenesis, accounting for up to 25% and 60% of endogenous glucose production...

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Detalles Bibliográficos
Autores principales: Nakamura, Motonobu, Satoh, Nobuhiko, Horita, Shoko, Nangaku, Masaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589488/
https://www.ncbi.nlm.nih.gov/pubmed/36299884
http://dx.doi.org/10.3389/fphar.2022.1015204