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Role of Repeated Conformational Transitions in Substrate Binding of Adenylate Kinase
[Image: see text] The catalytic cycle of the enzyme adenylate kinase involves large conformational motions between open and closed states. A previous single-molecule experiment showed that substrate binding tends to accelerate both the opening and the closing rates and that a single turnover event o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589722/ https://www.ncbi.nlm.nih.gov/pubmed/36222098 http://dx.doi.org/10.1021/acs.jpcb.2c05497 |