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Physiologically-based pharmacokinetic model for pulmonary disposition of protein therapeutics in humans
Lung related disorders like COPD and Asthma, as well as various infectious diseases, form a major therapeutic area which would benefit from a predictive and adaptable mathematical model for describing pulmonary disposition of biological modalities. In this study we fill that gap by extending the cro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589728/ https://www.ncbi.nlm.nih.gov/pubmed/36266517 http://dx.doi.org/10.1007/s10928-022-09824-w |