Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Exposome Can Promote a C > T Mutation in the Breast Cancer Predisposing Gene PALB2

Background: Deregulation of DNA methylation/demethylation reactions may be the source of C > T mutation via active deamination of 5-methylcytosine to thymine. Exposome, that is to say, the totality of exposures to which an individual is subjected during their life, can deregulate these reactions....

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Detalles Bibliográficos
Autores principales: Courant, Florestan, Bougras-Cartron, Gwenola, Abadie, Caroline, Frenel, Jean-Sébastien, Cartron, Pierre-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590087/
https://www.ncbi.nlm.nih.gov/pubmed/36278678
http://dx.doi.org/10.3390/epigenomes6040032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590087/
https://www.ncbi.nlm.nih.gov/pubmed/36278678
http://dx.doi.org/10.3390/epigenomes6040032

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