High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy

The pathophysiology of epilepsy underlies a complex network dysfunction between neurons and glia, the molecular cell type-specific contributions of which remain poorly defined in the human disease. In this study, we validated a method that simultaneously isolates neuronal (NEUN +), astrocyte (PAX6 +...

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Detalles Bibliográficos
Autores principales: Pai, Balagopal, Tome-Garcia, Jessica, Cheng, Wan Sze, Nudelman, German, Beaumont, Kristin G., Ghatan, Saadi, Panov, Fedor, Caballero, Elodia, Sarpong, Kwadwo, Marcuse, Lara, Yoo, Jiyeoun, Jiang, Yan, Schaefer, Anne, Akbarian, Schahram, Sebra, Robert, Pinto, Dalila, Zaslavsky, Elena, Tsankova, Nadejda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590125/
https://www.ncbi.nlm.nih.gov/pubmed/36274170
http://dx.doi.org/10.1186/s40478-022-01453-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590125/
https://www.ncbi.nlm.nih.gov/pubmed/36274170
http://dx.doi.org/10.1186/s40478-022-01453-1

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