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High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy
The pathophysiology of epilepsy underlies a complex network dysfunction between neurons and glia, the molecular cell type-specific contributions of which remain poorly defined in the human disease. In this study, we validated a method that simultaneously isolates neuronal (NEUN +), astrocyte (PAX6 +...
Autores principales: | Pai, Balagopal, Tome-Garcia, Jessica, Cheng, Wan Sze, Nudelman, German, Beaumont, Kristin G., Ghatan, Saadi, Panov, Fedor, Caballero, Elodia, Sarpong, Kwadwo, Marcuse, Lara, Yoo, Jiyeoun, Jiang, Yan, Schaefer, Anne, Akbarian, Schahram, Sebra, Robert, Pinto, Dalila, Zaslavsky, Elena, Tsankova, Nadejda M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590125/ https://www.ncbi.nlm.nih.gov/pubmed/36274170 http://dx.doi.org/10.1186/s40478-022-01453-1 |
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