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Soluble CD146, a biomarker and a target for preventing resistance to anti-angiogenic therapy in glioblastoma
RATIONALE: Glioblastoma multiforme (GBM) is a primary brain tumor with poor prognosis. The U.S. food and drug administration approved the use of the anti-VEGF antibody bevacizumab in recurrent GBM. However, resistance to this treatment is frequent and fails to enhance the overall survival of patient...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590138/ https://www.ncbi.nlm.nih.gov/pubmed/36274147 http://dx.doi.org/10.1186/s40478-022-01451-3 |