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Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common and malignant tumors in the digestive tract. Tumor Suppressor Candidate 3 (TUSC3) is one subunit of the endoplasmic reticulum Oligosaccharyl transferase (OST) complex, which plays an important role in N-glycosylation during the pro...

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Detalles Bibliográficos
Autores principales: Deng, Ruxia, Lu, Xiansheng, Hong, Chang, Cai, Rui, Wang, Ping, Xiong, Le, Wang, Xiaoyu, Chen, Qiaoyu, Lin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590144/
https://www.ncbi.nlm.nih.gov/pubmed/36274132
http://dx.doi.org/10.1186/s12967-022-03690-3