Significant variation in the performance of DNA methylation predictors across data preprocessing and normalization strategies

BACKGROUND: DNA methylation (DNAm)-based predictors hold great promise to serve as clinical tools for health interventions and disease management. While these algorithms often have high prediction accuracy, the consistency of their performance remains to be determined. We therefore conduct a systema...

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Detalles Bibliográficos
Autores principales: Ori, Anil P. S., Lu, Ake T., Horvath, Steve, Ophoff, Roel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590227/
https://www.ncbi.nlm.nih.gov/pubmed/36280888
http://dx.doi.org/10.1186/s13059-022-02793-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590227/
https://www.ncbi.nlm.nih.gov/pubmed/36280888
http://dx.doi.org/10.1186/s13059-022-02793-w

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