Role of harvest depth filtration in controlling product-related impurities for a bispecific antibody

BACKGROUND: Bispecific antibodies (BsAb) belong to a novel antibody category with advantages over traditional mono-specific therapeutic antibodies. However, product variants are also commonly seen during the production of BsAb, which poses significant challenges to downstream processing. In this stu...

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Detalles Bibliográficos
Autores principales: Espah Borujeni, Ehsan, Jin, Weixin, Shao, Chun, Chennamsetty, Naresh, Xu, Xuankuo, Ghose, Sanchayita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590317/
https://www.ncbi.nlm.nih.gov/pubmed/36299416
http://dx.doi.org/10.1093/abt/tbac023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590317/
https://www.ncbi.nlm.nih.gov/pubmed/36299416
http://dx.doi.org/10.1093/abt/tbac023

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