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Role of harvest depth filtration in controlling product-related impurities for a bispecific antibody
BACKGROUND: Bispecific antibodies (BsAb) belong to a novel antibody category with advantages over traditional mono-specific therapeutic antibodies. However, product variants are also commonly seen during the production of BsAb, which poses significant challenges to downstream processing. In this stu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590317/ https://www.ncbi.nlm.nih.gov/pubmed/36299416 http://dx.doi.org/10.1093/abt/tbac023 |