Swinhoeic acid from Potentilla fragarioides ameliorates high glucose-induced oxidative stress and accumulation of ECM in mesangial cells via Keap1-dependent activation of Nrf2

OBJECTIVES: Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes mellitus. Oxidative stress resulting from high glucose promotes accumulation of ECM and development of DN. Activation of Nrf2 could attenuate oxidative stress and following accumulation of ECM. To...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Huankai, Kong, Min, Du, Dan, Ai, Fengwei, Li, Jindong, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590439/
https://www.ncbi.nlm.nih.gov/pubmed/36259553
http://dx.doi.org/10.1080/13510002.2022.2134755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590439/
https://www.ncbi.nlm.nih.gov/pubmed/36259553
http://dx.doi.org/10.1080/13510002.2022.2134755

Ejemplares similares