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Origin and Spread of the ALDH2 Glu504Lys Allele

Gene polymorphism of acetaldehyde dehydrogenase 2 (ALDH2), a key enzyme for alcohol metabolism in humans, can affect catalytic activity. The ALDH2 Glu504Lys mutant allele has a high-frequency distribution in East Asian populations and has been demonstrated to be associated with an increased risk of...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaokai, Sun, Aijun, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590465/
https://www.ncbi.nlm.nih.gov/pubmed/36939783
http://dx.doi.org/10.1007/s43657-021-00017-y