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Toll-like receptor and cytokine expression throughout the bone marrow differs between patients with low- and high-risk myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are hematopoietic stem cell disorders, the pathogenesis of which involves enhanced immune signaling that promotes or selects for mutant hematopoietic stem and progenitor cells (HSPCs). In particular, toll-like receptor (TLR) expression and signaling are enhanced in MD...

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Detalles Bibliográficos
Autores principales: Paracatu, Luana Chiquetto, Monlish, Darlene A., Greenberg, Zev J., Fisher, Daniel A.C., Walter, Matthew J., Oh, Stephen T., Schuettpelz, Laura G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590644/
https://www.ncbi.nlm.nih.gov/pubmed/35367529
http://dx.doi.org/10.1016/j.exphem.2022.03.011