Cargando…
Toll-like receptor and cytokine expression throughout the bone marrow differs between patients with low- and high-risk myelodysplastic syndromes
Myelodysplastic syndromes (MDS) are hematopoietic stem cell disorders, the pathogenesis of which involves enhanced immune signaling that promotes or selects for mutant hematopoietic stem and progenitor cells (HSPCs). In particular, toll-like receptor (TLR) expression and signaling are enhanced in MD...
Autores principales: | Paracatu, Luana Chiquetto, Monlish, Darlene A., Greenberg, Zev J., Fisher, Daniel A.C., Walter, Matthew J., Oh, Stephen T., Schuettpelz, Laura G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590644/ https://www.ncbi.nlm.nih.gov/pubmed/35367529 http://dx.doi.org/10.1016/j.exphem.2022.03.011 |
Ejemplares similares
-
Contribution of Aberrant Toll Like Receptor Signaling to the Pathogenesis of Myelodysplastic Syndromes
por: Paracatu, Luana Chiquetto, et al.
Publicado: (2020) -
The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescence
por: Greenberg, Zev J., et al.
Publicado: (2023) -
The Role of Toll-Like Receptors in Hematopoietic Malignancies
por: Monlish, Darlene A., et al.
Publicado: (2016) -
The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes
por: Higgins, Cassandra B., et al.
Publicado: (2022) -
Pten Cell Autonomously Modulates the Hematopoietic Stem Cell Response to Inflammatory Cytokines
por: Porter, Shaina N., et al.
Publicado: (2016)