LigA formulated in AS04 or Montanide ISA720VG induced superior immune response compared to alum, which correlated to protective efficacy in a hamster model of leptospirosis

Leptospirosis is a zoonotic disease of global importance. The current vaccine provides serovar-specific and short-term immunity and does not prevent bacterial shedding in infected animals. Subunit vaccines based on surface proteins have shown to induce protection in an animal model. However, these p...

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Detalles Bibliográficos
Autores principales: Varma, Vivek P., Kadivella, Mohammad, Kumar, Ajay, Kavela, Sridhar, Faisal, Syed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590693/
https://www.ncbi.nlm.nih.gov/pubmed/36300125
http://dx.doi.org/10.3389/fimmu.2022.985802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9590693/
https://www.ncbi.nlm.nih.gov/pubmed/36300125
http://dx.doi.org/10.3389/fimmu.2022.985802

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