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Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial

BACKGROUND: Children with sickle cell anemia (SCA) in areas of Africa with endemic malaria transmission are commonly prescribed malaria chemoprevention. Chemoprevention regimens vary between countries, and the comparative efficacy of prevention regimens is largely unknown. METHODS AND FINDINGS: We e...

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Detalles Bibliográficos
Autores principales: Taylor, Steve M., Korwa, Sarah, Wu, Angie, Green, Cynthia L., Freedman, Betsy, Clapp, Sheila, Kirui, Joseph Kipkoech, O’Meara, Wendy P., Njuguna, Festus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9591057/
https://www.ncbi.nlm.nih.gov/pubmed/36215323
http://dx.doi.org/10.1371/journal.pmed.1004104