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The AGMK1-9T7 cell model of neoplasia: Evolution of DNA copy-number aberrations and miRNA expression during transition from normal to metastatic cancer cells

To study neoplasia in tissue culture, cell lines representing the evolution of normal cells to tumor cells are needed. To produce such cells, we developed the AGMK1-9T7 cell line, established cell banks at 10-passage intervals, and characterized their biological properties. Here we examine the evolu...

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Detalles Bibliográficos
Autores principales: Lewis, Andrew M., Thomas, Rachael, Breen, Matthew, Peden, Keith, Teferedegne, Belete, Foseh, Gideon, Motsinger-Reif, Alison, Rotroff, Daniel, Lewis, Gladys
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9591059/
https://www.ncbi.nlm.nih.gov/pubmed/36279283
http://dx.doi.org/10.1371/journal.pone.0275394