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ICAN: Interpretable cross-attention network for identifying drug and target protein interactions

Drug–target protein interaction (DTI) identification is fundamental for drug discovery and drug repositioning, because therapeutic drugs act on disease-causing proteins. However, the DTI identification process often requires expensive and time-consuming tasks, including biological experiments involv...

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Detalles Bibliográficos
Autores principales: Kurata, Hiroyuki, Tsukiyama, Sho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9591068/
https://www.ncbi.nlm.nih.gov/pubmed/36279284
http://dx.doi.org/10.1371/journal.pone.0276609