Microtubules restrict F-actin polymerization to the immune synapse via GEF-H1 to maintain polarity in lymphocytes

Immune synapse formation is a key step for lymphocyte activation. In B lymphocytes, the immune synapse controls the production of high-affinity antibodies, thereby defining the efficiency of humoral immune responses. While the key roles played by both the actin and microtubule cytoskeletons in the f...

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Detalles Bibliográficos
Autores principales: Pineau, Judith, Pinon, Léa, Mesdjian, Olivier, Fattaccioli, Jacques, Lennon Duménil, Ana-Maria, Pierobon, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592083/
https://www.ncbi.nlm.nih.gov/pubmed/36111670
http://dx.doi.org/10.7554/eLife.78330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592083/
https://www.ncbi.nlm.nih.gov/pubmed/36111670
http://dx.doi.org/10.7554/eLife.78330

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