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DNA Topoisomerase II-α Regulated by miR-22-5p Promotes Hepatocellular Carcinoma Invasion and Migration through the Hippo Pathway

DNA topoisomerases (TOPs) are dysregulated in various types of cancer. However, how TOP II-alpha (TOP2A) contributes to hepatocellular carcinoma (HCC) progression remains elusive. Cohort analysis revealed that the increased expression of TOP2A was associated with poor clinical outcomes and TOP2A was...

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Detalles Bibliográficos
Autores principales: Zhao, Haichao, Chen, Changzhou, Song, Huangqin, Qin, Rongyi, Wang, Xiaoxiao, He, Qizu, Li, Feng, Zhao, Haoliang, Li, Yanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592219/
https://www.ncbi.nlm.nih.gov/pubmed/36299605
http://dx.doi.org/10.1155/2022/4277254